Cellular plasticity in development and cancer
Centro de Biología Molecular “Severo Ochoa” CSIC-UAM (CBMSO)
DESCRIPTION OF THE OFFER
The goal of our research group is to understand how cellular identity is determined, and how it becomes deregulated in pathological conditions, such as cancer and congenital syndromes. We focus our research on the development and diseases of the immune system and, as experimental tools, we use: 1) genetically engineered mouse models (GEMMs) in which we modify the expression of transcription factors and epigenetic regulators, either normal or oncogenic, and 2) samples from patients with genetic syndromes.
Biomolecules & Cell D.