Virus engineering and Nanobiotechnology

SCIENTIFIC AREA
Molecular Virology
Center
Centro de Biología Molecular “Severo Ochoa” CSIC-UAM (CBMSO)
VACANCIES
1
CONTACT E-MAIL
avalbuena@cbm.csic.es
DESCRIPTION OF THE OFFER
Piece of HIV capsid lattice showing in-silico residue substitutions.

The completion of a Master's Thesis in Nanotechnology and Virus Biophysics is offered. In our group we try to understand the self-assembly of viruses. The knowledge of this process presents applications for the design of antiviral drugs and the use of capsids in Nanomedicine and Nanotechnology. The Master's Thesis focuses on the implementation of Computational methodology using Molecular Dynamics for the study of the HIV capsid. Virtual mutations of individual residues will be introduced into a partial capsid model to understand their role in the curvature of the capsid. This work, due to its computational nature, can be carried out independently of possible mobility restrictions in the next months.

MASTER
Biomolecules & Cell D.
Molecular Biomedicine
Biotechnology
SUPERVISOR TFM
Alejandro Valbuena