PhD position available in Rome, Sapienza University - Marie Curie Innovative Training Network (ITN) H2020 Programme

                                           PhD position available in Rome, Sapienza University

                             Marie Curie Innovative Training Network (ITN) H2020 Programme,

             “circular RNA biology Training Network: from biogenesis to biomarkers” circRTrain

Lab of Prof. Irene Bozzoni

Job Summary:

circRTrain is a Marie Curie Innovative Training Network (ITN) funded by the European Commission within the Horizon 2020  program. This network of 7 academic research institutions/universities and 6 companies will provide cross-disciplinary training in experimental and computational biology for a new generation of researchers who will exploit the power of emerging technological platforms to decipher the biology of circular RNAs.

Job Description:

The lab of Irene Bozzoni, placed in Rome at the Sapienza University, will focus on: circRNA function in muscle and motor neuron differentiation and related diseases

The objectives are:

a) study the role of  circRNAs in cell differentiation;

b) analyze whether deregulation of circRNAs is involved in the pathogenesis of different muscle (Duchenne Muscular Dystrophy, Rhabdomyosarcoma) or neurodegenerative (Amyothrophic Lateral Sclerosis) diseases;

c) dissect circRNA function through the production of cellular and animal KO model systems;

d) analyze the ability of circRNAs to be translated (Legnini I. et al, Mol Cell, 2017)

e) set up conditions for circRNA pull down and purification of interacting factors.

Contact:

• irene.bozzoni@uniroma1.it
• https://euraxess.ec.europa.eu/jobs/359461 
• https://circrtrain.eu/

Starting date: early 2019