Physiopathology of atherogenesis
Pathophysiology and Therapy of Immune and Inflammatory Diseases
Instituto de Investigaciones Biomédicas “Alberto Sols” CSIC-UAM (IIBM)
DESCRIPTION OF THE OFFER
Immunobiology of atherotrombosis
According to the World Health Organization, cardiovascular diseases are the first cause of death globally and atherosclerosis underpins most of the incidence. It is a chronic disease characterized by progressive retention of lipids in the arterial wall and an exacerbated inflammatory response. The TFM will help establishing a role for the immune receptor nucleotide-binding oligomerization domain 1 (NOD1) in the context of atherosclerosis. To perform this project, our lab will provide flow cytometry, immunofluorescence, mouse genetics and in vitro and in vivo functional assays.
Silvia González Ramos