Virus-host interaction

We are interested in studying the interaction between viruses and the host innate immune response, and to characterize possible molecular mechanisms used by viruses to counteract the effect of IFN. We are currently working with two viral systems, infectious bursal disease virus (IBDV), a dsRNA virus that affect young chickens, causing a drastic immunosuppression, or can even result in the death of the animal and toroviruses, ssRNA viruses that causes enteric infections in different species of domestic animals, and. Our work is aimed at understanding the molecular basis of IBDV and torovirus pathogenesis.