Molecular mechanisms of nephrotoxicity and new experimental therapies in renal disease
Pathophysiology and Therapy of Immune and Inflammatory Diseases
Hospital Universitario Fundación Jiménez Díaz
DESCRIPTION OF THE OFFER
We are interested to know the pathophysiological basis of nephrotoxicity, with a special focus on the inflammatory process, which could also explain the course of common acute and chronic renal diseases. Thus, in several experimental in vitro and animal models we try to identify, through biochemical and cellular approaches, molecular mediators and potential therapeutic and diagnostic molecular targets to treat the renal disease. The analysis of human biological samples is also included in the experimental strategy. As part of an active project, we are blocking inflammatory cytokines in order to establish their role in human renal pathology and also to study their behavior as biomarkers of renal disease.
Biomolecules & Cell D.