Lab 3D (Development, Differentiation and Degeneration)
Pathophysiology and Therapy of Neurological and Neuromuscular Diseases
Centro de Investigaciones Biológicas CSIC (CIB)
DESCRIPTION OF THE OFFER
Retinitis Pigmentosa is a heterogeneous group of inherited retinal dystrophies characterized by the progressive loss of vision leading to blindness. It is unpreventable and incurable rare disease. Our group is focused in developing treatments that attenuate of photoreceptor cell death and preserve the visual function. By increasing the comprehension of the early events taking place in a mouse model of Retinitis Pigmentosa we aim to identify novel therapeutic targets. We employ retinal organotipic cultures as well as in vivo interventions to characterize the molecular and cellular interactions occurring in the dystrophic retina. We consider neuroprotection a tool to know better the basis of the disease, but also a goal to fulfill a medical need.