Epithelial Polarity Group
Cellular Organization and Control
Centro de Biología Molecular “Severo Ochoa” CSIC-UAM (CBMSO)
DESCRIPTION OF THE OFFER
Our group is part of the Department of Developmental Biology and Differentiation at the Centro de Biología Molecular Severo Ochoa (CBMSO), located at the Universidad Autónoma de Madrid (UAM) campus, in Madrid, Spain.
The focus of our research is the biology of epithelial organs during disease and development. Cell polarity is at the crossroads of differentiation and growth, and loss of cell polarity is a hallmark of cancer and other relevant diseases. Thus, our approach currently lies in the study of the cellular mechanisms related to the establishment of cell polarity in epithelial tissues. We are interested in the use of close-to-physiological models ranging from three-dimensional organotypic culture systems, to in vivo studies in vertebrates, such as zebrafish and mice.
Biomolecules & Cell D.